DIABESITY & NUTRIGENOMICS
to start with: DIABESITY
SOME BOOKS:
Diabesity: A Doctor and Her Patients on the Front Lines of
the Obesity-Diabetes Epidemic
Francine Ratner Kaufman |
Go to:
This site, and the following sites are advertisements for products/services - that I hope you find interesting enough to want to buy.
Sales, of course, usually pay commissions.......
The information for each site is taken from that site.
Diabesity: The Obesity-Diabetes Epidemic That Threatens
America--And What We Must Do to Stop It
Francine R. Kaufman M.D.
Go to:
|
The Blood Sugar Solution: The UltraHealthy Program for Losing Weight, Preventing Disease, and Feeling Great Now!
Mark Hyman M.D. |
Go To:
http://rcm.amazon.com/e/cm?t=wwwmaxmusclel-20&o=1&p=8&l=as1&asins=031612737X&ref=qf_sp_asin_til&fc1=000000&IS2=1<1=_blank&m=amazon&lc1=0000FF&bc1=000000&bg1=FFFFFF&f=ifr
DETAILS:
by Mark Hyman:
This is a discussion about a modern epidemic, a deadly disease that one of every two of you have, a disease that's making you fat, sick and will kill you, but 90 percent of you don't even know you have it.
This disease is diabesity, the continuum of abnormal biology that ranges from mild insulin resistance to full-blown diabetes.
(See the three books above... .)
To explain the real causes of diabesity and provide eight steps you can take to reverse this disease starting today:
The Real Causes of Diabesity
The entire spectrum of diabesity including all of its complications -- diabetes, elevated blood sugar, blood pressure and cholesterol -- are simply downstream symptoms that result from problems with diet, lifestyle, and environmental toxins interacting with our unique genetic susceptibilities.
Those are the real causes of diabesity.
And the reason these dietary and lifestyle factors lead to diabesity is because they create a condition known as insulin resistance. Contrary to what most people think, Type 2 diabetes is a disease of too much, not too little, insulin. Insulin is the real driver of problems with diabesity.
When your diet is full of empty calories and an abundance of quickly-absorbed sugars, liquid calories and carbohydrates (like bread, pasta, rice and potatoes), your cells slowly become resistant to the effects of insulin and need more and more to do the same job of keeping your blood sugar even. Thus you develop insulin resistance. A high insulin level is the first sign of a problem. The higher your insulin levels are, the worse your insulin resistance. Your body starts to age and deteriorate. In fact, insulin resistance is the single most important phenomenon that leads to rapid and premature aging and all its resultant diseases, including heart disease, stroke, dementia and cancer.
As your insulin levels increase it leads to an appetite that is out of control, increasing weight gain around the belly, more inflammation and oxidative stress, and myriad downstream effects including high blood pressure, high cholesterol, low HDL, high triglycerides, weight gain around the middle, thickening of the blood and increased risk of cancer, Alzheimer's and depression. These are all a result of insulin resistance and too much insulin. Elevated blood sugar is not the source of the problem.
And because insulin resistance (and diabesity) are a direct outcome of diet and lifestyle, the condition is 100 percent reversible in the vast majority of cases. Most people just need to eliminate the things that are sending their biology out of balance and include what's needed to help the body rebalance itself. For most, the interventions required are extremely simply and extraordinarily effective.
8 Steps to Reversing Diabesity:
In my new book, "The Blood Sugar Solution," now available, I outline a comprehensive 8-week plan for overcoming diabesity in all its forms. Here is a sneak preview of the steps outlined in the book:
1. Get the right tests. Most doctors focus on fasting blood sugar. This is actually a poor indicator of diabesity. The best test to tease out the condition is an insulin response test where insulin levels are measured fasting and then 1 and 2 hours after a glucose drink. Demand this test from your doctor.
2. Get smart about nutrition. Despite the media hype and the seeming confusion amongst doctors, the basics of nutrition are extremely simple. Eliminate sugar and processed carbohydrates, include whole real foods like lean protein (chicken or fish), veggies, nuts, seeds, beans and whole grains.
3. Get the right supplements. There has recently been a frenzy of negative reports about supplements. Most of them are unfounded. Supplements are an essential part of treating diabesity. A good multivitamin, vitamin D, fish oil and special blood sugar balancing nutrients like alpha lipoic acid, chromium polynicotinate, biotin, cinnamon, green tea catechins and glucomannan should also be included.
4. Get relaxed. Stress is a major unrecognized contributor to insulin resistance and blood sugar imbalance. Push your pause button every day with deep breathing, visualization, yoga and other relaxation techniques.
5. Get moving. Aside from changing your diet, exercise is probably the single best medication for diabesity. Walk for at least 30 minutes every day. For some, 30-60 minutes of more vigorous aerobic exercise 4-6 times a week may be necessary.
6. Get clean and green. Environmental toxins also contribute to diabesity. Filter your water, look for green cleaning products and avoid plastics when you can.
7. Get personal. While the steps above will address 80 percent of the problems with diabesity, some may need to take additional steps to optimize key areas of their biology. Remember, the medicine of the future is personal medicine. Seek out your own biological imbalances and look for ways to address them.
8. Get connected. Research is beginning to show that we get better more effectively when we get together. Invite your friends, families and neighbors to change their diets and lifestyle along with you. Together we can all take back our health.
The book: "The Blood Sugar Solution," is where where I outline all of the social, economic, biological and medical underpinnings of this health epidemic and provide an 8-week, step-by-step system that will allow you to dig deep into your own biology and heal even the most severe cases of diabesity. This is it.
by Mark Hyman:
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Now, a change to an associated topic - to put the two together, the implications are immense.....................
Nutritional genomics
Nutritional genomics is a science studying the relationship between human genome, nutrition and health.It can be divided into two disciplines:
- Nutrigenomics: studies the effect of nutrients on health through altering genome, proteome, metabolome and the resulting changes in physiology.
- Nutrigenetics: studies the effect of genetic variations on the interaction between diet and health with implications to susceptible subgroups. More specifically, nutrigenomics studies how individual differences in genes influence the body's response to diet and nutrition. For example, people with an enzyme deficiency caused by mutations in the enzyme phenylalanine hydroxylase cannot metabolize foods containing the amino acid phenylalanine and must modify their diets to minimize consumption. With modern genomic data, severe gene mutations with less severe effects are being explored to determine whether dietary practices can be more closely personalized to individual genetic profiles. However, there have been few validated studies for these kinds of classical gene mutation effect.
a good book:
Nutritional Genomics: The Impact of Dietary Regulation of
Gene Function on Human Disease
Wayne R. Bidlack
Go to:
Nutrigenomics
Nutrigenomics refers to the prospective analysis of differences among nutrients in the regulation of gene expression i.e., it studies the effect of nutrients on the genome, proteome, and metabolome. It involves the application of high-throughput genomic tools such as DNA microarray technology in nutrition research. Nutrigenomics is a discovery science which aims at understanding how nutrition influences metabolic pathways and homeostatic control and how this regulation is disturbed in the early phase of a diet-related disease.Gene-diet-disease interaction
97% of the genes known to be associated with human diseases result in monogenic diseases, i.e. a mutation in one gene is sufficient to cause the disease. Modifying the dietary intake can prevent some monogenic diseases. One example is phenylketonuria, a genetic disease characterized by a defective phenylalanine hydroxylase enzyme, which is normally responsible for the metabolism of phenylalanine to tyrosine. This results in the accumulation of phenylalanine and its breakdown products in the blood and the decrease in tyrosine, which increases the risk of neurological damage and mental retardation. Phenylalanine-restricted tyrosine-supplemented diets are a means to nutritionally treat this monogenic disease.In contrast, many common diseases, such as obesity, cancer, diabetes, and cardiovascular diseases, are polygenic diseases, i.e. they arise from the dysfunction in a cascade of genes, and not from a single mutated gene. Dietary intervention to prevent the onset of such diseases is a complex and ambitious goal.
Recently, it was discovered that the health effects of food compounds are related mostly to specific interactions on molecular level, i.e. dietary constituents participate in the regulation of gene expression by modulating the activity of transcription factors, or through the secretion of hormones that in turn interfere with a transcription factor. -Wiki....
Applications
A number of genetic variations have been shown to increase the susceptibility to diet-related diseases. These include variants that have been associated with Type 2 diabetes mellitus, obesity, cardiovascular diseases, some autoimmune diseases and cancers. Nutrigenetics aims to study these susceptible genes and provide dietary interventions for individuals at risk of such diseases. Some examples are shown below.There is considerable information about these topics on the net - take a look............................
The implications are life changing......................................
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For example, this comment by Michael Cutler, M.D.
Editor, Easy Health Options®
"Due to biochemical reactions in your body that occur with every type of food you eat on a daily basis, some foods age you FASTER than your real age, while other foods help to FIGHT aging.
Eat the wrong foods regularly, and you can look and feel 10 or more years OLDER than your real age (not fun!) ... but eat the right foods, and over time, you can start to look 5-10 years YOUNGER than your real age.
Three of the processes that go on inside your body that have a MAJOR impact on your rate of aging are called "glycation", "inflammation", and "oxidation". When we talk about aging, we're not just talking about wrinkles on your skin or how thick your hair is... we're also talking about factors that you can't see, such as how well your organs function, and whether your joints are degrading.
Yes, I'm sure you'll agree this is much more important than just how you look superficially (although we'll show you how to improve BOTH!)
With the title of this article, ( The #1 WORST Food that CAUSES Faster Aging ), you might have guessed that obvious answers like sugar or trans fat would be what we talk about in this article. Yes, those are bad, but I want to discuss another food that ages your body faster than normal... and it's one that you might not expect!
So let's dig right in and I'll show you how your rate of aging can be directly related to the foods you might eat every day, and how to protect yourself...
The #1 WORST food that ages you faster:Wheat based foods (yes, even "whole wheat")
Before I tell you why wheat can actually speed up the aging process in your body, let's clarify some simple biochemistry in your body...
This deals with "glycation" in your body, and substances called Advanced Glycation End Products (AGEs). These nasty little compounds called AGEs speed up the aging process in your body including damage over time to your organs, your joints, and of course, wrinkled skin.
So with that said, what is one of the biggest factors that increase production of AGEs inside your body? This may surprise you, but high blood sugar levels over time dramatically increase age-accelerating AGEs in your body. This is why type 2 diabetics many times appear that they have not aged well and look older than their real age. But this age-increasing effect is not just limited to diabetics.
So, let's get back to how "whole wheat" relates to this...
Here is a little-known fact that's often covered up by the massive marketing campaigns by giant food companies that want you to believe that "whole wheat" is healthy for you... but the fact is that wheat contains a very unusual type of carbohydrate (not found in other foods) called Amylopectin-A, which has been found in some tests to spike your blood sugar higher than even pure table sugar.
In fact, amylopectin-A (from wheat) raises your blood sugar more than almost any other carbohydrate source on earth based on blood sugar response testing.
This means that wheat-based foods such as breads, bagels, cereals, muffins, and other baked goods often cause much higher blood sugar levels than most other carbohydrate sources. As you know now, the higher your average blood sugar levels are over time, the more AGEs are formed inside your body, which makes you age FASTER.
You've probably heard about the potential health-damaging effects of gluten (also found in wheat) in the news recently, but this blood sugar aspect we just covered is not talked about that often, and is yet another reason to reduce or eliminate wheat-based foods in your diet. Your body will thank you by aging slower and looking YOUNGER! And losing bodyfat is typically a fun side effect of eliminating or reducing wheat in your diet!
Another problem with wheat-based foods and aging...
As it turns out, baked wheat products contain carcinogenic chemicals called acrylamides that form in the browned portion of breads, cereals, muffins, etc. These carcinogenic acrylamides have been linked in studies to possible increased risk of cancer and accelerated aging. Note that acrylamides are also found in high levels in other browned carbohydrate sources such as french fries or any other browned starchy foods.
Don't worry though... There's a trick that you can use to protect yourself from these carcinogenic acrylamides, and it has to do with eating the RIGHT foods that COUNTERACT damage from these nasty chemicals.
Other foods to watch out for that can increase aging in your body include corn-based foods that also disrupt blood sugar highly (corn cereals, corn chips, corn syrup), soybean oil and other "vegetable" oils that contain excessively refined and processed fats that cause inflammation in your body, and also excess sugars from candies, cakes, and sweetened drinks."
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more info at:
about phytic acid:
http://4-my-best-life.blogspot.com.au/2014/08/phytic-acid-friend-or-foe.html
http://4-my-best-life.blogspot.com.au/2013/01/making-choices.html
also:
http://4-my-best-life.blogspot.com.au/2013/01/u-dont-have-to-hide.html
http://4-my-best-life.blogspot.com.au/2013/02/fat-loss.html
http://4-my-best-life.blogspot.com.au/2013/01/health-master.html
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You probably read this on some sort of computing device:
Such
things need maintenance. There is a totally inappropriate sexist joke,
in some quarters, about a little old 'person'' who wondered why the car
would not go. When asked about when maintenance was last done - "What
is that?" .............................................
Personal experience:
Yes, I lost my most precious photos. Because I did not have them copied, or backed up.
I now have them, (what I have left!!), copied, and backed up - I used:
My PC Backup: http://track.mypcbackup.com/?hash=960c4a62
Please back-up your precious documents - don't loose them, like I did.
And, please tell a friend - may save their .........
(The
way it happened, wasn't even someone hacking! Some computer "tech" was
eliminating some old files from my computer - to help it run faster.
Bingo!! Photos gone!!!)
Concerning hacking.....
Did
you know that there are now more than 220,000 new attempts to interfere
with computers, created every day. Most are destroyed pretty quickly.
BUT>>>>>>>>> NOT all of them
Made me rethink my computer protection.
It is now, not a question of "ïf" they will take out my computer, it is a question of "when".........
So, I now use, and I recommend for you:
PC DEFENDER: http://gojvz.com/c/48000/20846
and, BLOG DEFENDER: http:com/c/48000/20094//gojvz.
and, this one is good:
UniBLUE speed up my computer:
http://www.uniblue.com/cm/general/speedupmypc/spunit/download/?aff=25435
You can get free hosting here:
http://www.000webhost.com/680396.html
You can get free hosting here:
http://www.000webhost.com/680396.html
Some old sage said something about being prepared, & vigilant.........yes......
As you know, sales may generate commissions......
IMPORTANT NOTICE:
You may have noticed that I have not asked you for your email......
I do not send pesty repeat emails to try & get you to buy........
(I personally find them annoying - and I don't do it to you.........)
In return, may I ask a favor??
If you would care to reconsider the information above, and purchase something - it would make us both happy!!
YOU ARE WORTH IT!!!!!
And, thank-you for telling your friends.....................
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